Sarcoidosis Approach

Sarcoidosis is a granulomatous disease of unclear etiology with the potential affection of major organs. It most commonly affects the lungs, skin, eyes, and lymph nodes. Less frequent, though possibly underestimated, manifestations are rheumatic and renal disease. As a systemic disease, it can present in numerous ways and mimic many other conditions, including infections and cancer. While it has been proposed that an abnormal immunologic response to antigens leads to granulomatous inflammation in genetically predisposed individuals, much has to be learned.

Sarcoidosis can present as an acute and self-limiting disease or progress to a chronic and potentially debilitating disorder. The acute form, Löfgren's syndrome, typically presents with an ankle periarthritis, bilateral hilar lymphadenopathy, and erythema nodosum. The chronic type of the disease may be less straightforward to identify: it may present with relapsing episodes of uveitis, mimic asthma with a dry cough, or present with cervical lymphadenopathy as the first symptom..

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Nimmi Anna
Journal Manager
Allied Journal of Medical Research
Email: medicalresearch@emedsci.com
https://www.alliedacademies.org/allied-journal-of-medical-research/